Gene information
Official symbol PTH
Official full name parathyroid hormone
Gene type protein-coding gene
Chromosome11p15.3
Alias symbolPTH1
Gene familyReceptor ligands
Resources
Entrez Gene 5741
HGNC HGNC:9606
Ensembl ENSG00000152266
Vega OTTHUMG00000165785
UCSC uc057zha.1
GO terms: 104 records
GO Description Category LogP Number of genes Detail
GO:0001501 skeletal system development GO Biological Processes -17.2073293 69 More
GO:0001503 ossification GO Biological Processes -16.3087139 28 More
GO:0001664 G protein-coupled receptor binding GO Molecular Functions -22.7408810 35 More
GO:0001894 tissue homeostasis GO Biological Processes -10.3152206 20 More
GO:0005179 hormone activity GO Molecular Functions -33.3562443 33 More
GO:0005979 regulation of glycogen biosynthetic process GO Biological Processes -6.48443546 10 More
GO:0006109 regulation of carbohydrate metabolic process GO Biological Processes -13.1742479 35 More
GO:0006873 cellular ion homeostasis GO Biological Processes -10.3574947 26 More
GO:0006875 cellular metal ion homeostasis GO Biological Processes -10.3879696 23 More
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway GO Biological Processes -9.16710904 33 More
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway GO Biological Processes -6.95524830 22 More
GO:0007202 activation of phospholipase C activity GO Biological Processes -4.61361828 8 More
GO:0007264 small GTPase mediated signal transduction GO Biological Processes -2.76738893 22 More
GO:0007265 Ras protein signal transduction GO Biological Processes -1.87357952 15 More
GO:0007584 response to nutrient GO Biological Processes -29.4823239 48 More
GO:0009150 purine ribonucleotide metabolic process GO Biological Processes -1.73087600 10 More
GO:0009187 cyclic nucleotide metabolic process GO Biological Processes -4.57029927 9 More
GO:0009259 ribonucleotide metabolic process GO Biological Processes -1.59291266 10 More
GO:0009410 response to xenobiotic stimulus GO Biological Processes -32.6021211 82 More
GO:0009725 response to hormone GO Biological Processes -49.1091700 138 More
GO:0009755 hormone-mediated signaling pathway GO Biological Processes -4.05849698 16 More
GO:0009991 response to extracellular stimulus GO Biological Processes -42.2178323 102 More
GO:0010035 response to inorganic substance GO Biological Processes -29.1720710 89 More
GO:0010038 response to metal ion GO Biological Processes -20.5090881 61 More
GO:0010675 regulation of cellular carbohydrate metabolic process GO Biological Processes -9.60411715 27 More
GO:0010676 positive regulation of cellular carbohydrate metabolic process GO Biological Processes -6.37680507 13 More
GO:0010827 regulation of glucose transmembrane transport GO Biological Processes -18.4601079 28 More
GO:0010828 positive regulation of glucose transmembrane transport GO Biological Processes -9.82015489 15 More
GO:0010906 regulation of glucose metabolic process GO Biological Processes -10.3110629 25 More
GO:0010907 positive regulation of glucose metabolic process GO Biological Processes -8.00848642 13 More
GO:0010962 regulation of glucan biosynthetic process GO Biological Processes -6.48443546 10 More
GO:0019693 ribose phosphate metabolic process GO Biological Processes -1.52492811 10 More
GO:0019725 cellular homeostasis GO Biological Processes -21.1508273 85 More
GO:0030003 cellular cation homeostasis GO Biological Processes -9.22969208 24 More
GO:0030278 regulation of ossification GO Biological Processes -11.2759455 26 More
GO:0030279 negative regulation of ossification GO Biological Processes -7.69659659 12 More
GO:0030282 bone mineralization GO Biological Processes -8.89624301 10 More
GO:0030500 regulation of bone mineralization GO Biological Processes -10.1371537 13 More
GO:0030501 positive regulation of bone mineralization GO Biological Processes -4.86040077 10 More
GO:0030502 negative regulation of bone mineralization GO Biological Processes -6.65436623 6 More
GO:0030545 signaling receptor regulator activity GO Molecular Functions -87.4728446 102 More
GO:0030546 signaling receptor activator activity GO Molecular Functions -90.4065983 101 More
GO:0031214 biomineral tissue development GO Biological Processes -8.35916144 12 More
GO:0031667 response to nutrient levels GO Biological Processes -41.8130555 98 More
GO:0032330 regulation of chondrocyte differentiation GO Biological Processes -3.54364153 9 More
GO:0032331 negative regulation of chondrocyte differentiation GO Biological Processes -3.67847337 4 More
GO:0032870 cellular response to hormone stimulus GO Biological Processes -24.7707938 79 More
GO:0032881 regulation of polysaccharide metabolic process GO Biological Processes -7.60302561 13 More
GO:0032885 regulation of polysaccharide biosynthetic process GO Biological Processes -7.40593429 12 More
GO:0033273 response to vitamin GO Biological Processes -22.1296854 31 More
GO:0033280 response to vitamin D GO Biological Processes -11.9382575 14 More
GO:0034762 regulation of transmembrane transport GO Biological Processes -31.7284805 100 More
GO:0034764 positive regulation of transmembrane transport GO Biological Processes -18.2616571 46 More
GO:0043255 regulation of carbohydrate biosynthetic process GO Biological Processes -8.87798147 21 More
GO:0043467 regulation of generation of precursor metabolites and energy GO Biological Processes -10.8295915 27 More
GO:0045453 bone resorption GO Biological Processes -4.37707433 7 More
GO:0045471 response to ethanol GO Biological Processes -15.9991788 20 More
GO:0045596 negative regulation of cell differentiation GO Biological Processes -26.9785067 101 More
GO:0045725 positive regulation of glycogen biosynthetic process GO Biological Processes -5.96315455 7 More
GO:0045778 positive regulation of ossification GO Biological Processes -4.90193440 11 More
GO:0045913 positive regulation of carbohydrate metabolic process GO Biological Processes -10.1978214 20 More
GO:0046324 regulation of glucose import GO Biological Processes -14.8736114 22 More
GO:0046326 positive regulation of glucose import GO Biological Processes -7.69659659 12 More
GO:0046849 bone remodeling GO Biological Processes -4.21089449 9 More
GO:0048018 receptor ligand activity GO Molecular Functions -91.0736151 101 More
GO:0048771 tissue remodeling GO Biological Processes -15.8777137 28 More
GO:0048871 multicellular organismal homeostasis GO Biological Processes -14.5562171 53 More
GO:0048872 homeostasis of number of cells GO Biological Processes -12.0072872 22 More
GO:0048873 homeostasis of number of cells within a tissue GO Biological Processes -5.73116566 9 More
GO:0050801 ion homeostasis GO Biological Processes -12.0812968 60 More
GO:0051345 positive regulation of hydrolase activity GO Biological Processes -19.7369783 79 More
GO:0051427 hormone receptor binding GO Molecular Functions -9.65736435 9 More
GO:0051428 peptide hormone receptor binding GO Molecular Functions -4.01931275 4 More
GO:0055062 phosphate ion homeostasis GO Biological Processes -3.41433421 5 More
GO:0055065 metal ion homeostasis GO Biological Processes -12.9426258 29 More
GO:0055074 calcium ion homeostasis GO Biological Processes -10.3600555 19 More
GO:0055080 cation homeostasis GO Biological Processes -11.5718912 30 More
GO:0055081 anion homeostasis GO Biological Processes -3.50343693 8 More
GO:0055082 cellular chemical homeostasis GO Biological Processes -17.6289728 71 More
GO:0060249 anatomical structure homeostasis GO Biological Processes -12.3640817 24 More
GO:0061035 regulation of cartilage development GO Biological Processes -4.43006301 12 More
GO:0061037 negative regulation of cartilage development GO Biological Processes -4.61361828 8 More
GO:0062012 regulation of small molecule metabolic process GO Biological Processes -26.8746473 69 More
GO:0062013 positive regulation of small molecule metabolic process GO Biological Processes -17.9792910 37 More
GO:0070167 regulation of biomineral tissue development GO Biological Processes -10.3239090 23 More
GO:0070168 negative regulation of biomineral tissue development GO Biological Processes -8.43961427 8 More
GO:0070169 positive regulation of biomineral tissue development GO Biological Processes -4.08950781 6 More
GO:0070663 regulation of leukocyte proliferation GO Biological Processes -26.8242532 37 More
GO:0070665 positive regulation of leukocyte proliferation GO Biological Processes -21.5362473 27 More
GO:0070848 response to growth factor GO Biological Processes -40.6139195 102 More
GO:0070873 regulation of glycogen metabolic process GO Biological Processes -6.66615417 11 More
GO:0070875 positive regulation of glycogen metabolic process GO Biological Processes -5.72938190 7 More
GO:0071774 response to fibroblast growth factor GO Biological Processes -7.87961599 11 More
GO:0072503 cellular divalent inorganic cation homeostasis GO Biological Processes -7.40235615 16 More
GO:0072506 trivalent inorganic anion homeostasis GO Biological Processes -3.41433421 5 More
GO:0072507 divalent inorganic cation homeostasis GO Biological Processes -10.6286093 21 More
GO:0097190 apoptotic signaling pathway GO Biological Processes -11.7839485 23 More
GO:0097305 response to alcohol GO Biological Processes -17.4096682 46 More
GO:0098771 inorganic ion homeostasis GO Biological Processes -12.1048319 31 More
GO:0110148 biomineralization GO Biological Processes -9.16361193 13 More
GO:0110149 regulation of biomineralization GO Biological Processes -10.9748263 24 More
GO:0110150 negative regulation of biomineralization GO Biological Processes -8.31494447 8 More
GO:0110151 positive regulation of biomineralization GO Biological Processes -4.74345761 11 More
GO:1902930 regulation of alcohol biosynthetic process GO Biological Processes -4.27715369 6 More
KEGG pathways: 3 records
KEGG Description Category LogP Number of genes Detail
hsa04080 Neuroactive ligand-receptor interaction KEGG Pathway -22.6219922 65 More
hsa04928 Parathyroid hormone synthesis, secretion and action KEGG Pathway -3.30201840 7 More
hsa05323 Rheumatoid arthritis KEGG Pathway -22.3868189 23 More
Drug-Gene interaction
view
Related drugs: 17 records
Drug name Interaction type Source PMID View
aspirin NCI 4004906 view
atenolol NCI 2649632 view
azathioprine NCI 2216934 view
calcitonin NCI 227233 view
clomiphene NCI 2322693 view
hydroxyurea NCI 30863846643680 view
ibandronic acid NCI 16366420 view
lamivudine NCI 16171525 view
lycopene NCI 12935316 view
midazolam NCI 15657568 view
penicillamine NCI 3137774 view
phenobarbital NCI 1490499 view
premarin NCI 2850907 view
puromycin NCI 1328752 view
ranitidine NCI 38782372864665 view
teriparatide TTD view
trilostane NCI 16300115 view
Related studies: 3 records
Molecular factor Omics type Application Objective MI type Reference
parathyroid hormone proteomics acute myocardial infarction[diagnosis] acute myocardial infarction Ljunghall S et al. Exp Clin Endocrinol. 1986
parathyroid hormone proteomics myocardial infarction[diagnosis] myocardial infarction Tagawa M et al. PLoS One. 2014
parathyroid hormone proteomics vitamin D deficiency[prognosis (bad)] acute myocardial infarction Aleksova A et al. Int J Vitam Nutr Res. 2015
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